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The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development
Bone morphogenetic proteins (BMPs) are crucial regulators of chondrogenesis. BMPs transduce their signals through three type I receptors: BMPR1A, BMPR1B, and ACVR1/ALK2. Fibrodysplasia ossificans progressiva (FOP), a rare disorder characterized by progressive ossification of connective tissue, is ca...
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| Pubblicato in: | J Bone Miner Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376569/ https://ncbi.nlm.nih.gov/pubmed/25413979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2385 |
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