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The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development

Bone morphogenetic proteins (BMPs) are crucial regulators of chondrogenesis. BMPs transduce their signals through three type I receptors: BMPR1A, BMPR1B, and ACVR1/ALK2. Fibrodysplasia ossificans progressiva (FOP), a rare disorder characterized by progressive ossification of connective tissue, is ca...

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Detalhes bibliográficos
Publicado no:J Bone Miner Res
Main Authors: Rigueur, Diana, Brugger, Sean, Anbarchian, Teni, Kim, Jong Kil, Lee, Yoo Jin, Lyons, Karen
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376569/
https://ncbi.nlm.nih.gov/pubmed/25413979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2385
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