Bone Marrow Derived Mesenchymal Stromal Cells Harness Purinergenic Signaling to Tolerize Human Th1 Cells In Vivo

The use of bone marrow derived mesenchymal stromal cells (BMSC) in the treatment of alloimmune and autoimmune conditions has generated much interest, yet an understanding of the therapeutic mechanism remains elusive. We therefore explored immune modulation by a clinical-grade BMSC product in a model...

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Publicat a:Stem Cells
Autors principals: Amarnath, Shoba, Foley, Jason E., Farthing, Don E., Gress, Ronald E., Laurence, Arian, Eckhaus, Michael A., Métais, Jean-Yves, Rose, Jeremy J., Hakim, Frances T., Felizardo, Tania C., Cheng, Austin V., Robey, Pamela G., Stroncek, David E., Sabatino, Marianna, Battiwalla, Minoo, Ito, Sawa, Fowler, Daniel H., Barrett, Austin J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376558/
https://ncbi.nlm.nih.gov/pubmed/25532725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1934
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