Methamphetamine Self-Administration in Mice Decreases GIRK Channel-Mediated Currents in Midbrain Dopamine Neurons

BACKGROUND: Methamphetamine is a psychomotor stimulant with abuse liability and a substrate for catecholamine uptake transporters. Acute methamphetamine elevates extracellular dopamine, which in the midbrain can activate D2 autoreceptors to increase a G-protein gated inwardly rectifying potassium (G...

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Bibliographic Details
Published in:Int J Neuropsychopharmacol
Main Authors: Sharpe, Amanda L., Varela, Erika, Bettinger, Lynne, Beckstead, Michael J.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376542/
https://ncbi.nlm.nih.gov/pubmed/25522412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu073
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