Ethanol Exposure Induces Neonatal Neurodegeneration by Enhancing CB1R Exon1 Histone H4K8 Acetylation and Up-regulating CB1R Function causing Neurobehavioral Abnormalities in Adult Mice

BACKGROUND: Ethanol exposure to rodents during postnatal day 7 (P7), which is comparable to the third trimester of human pregnancy, induces long-term potentiation and memory deficits. However, the molecular mechanisms underlying these deficits are still poorly understood. METHODS: In the present stu...

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Detalhes bibliográficos
Publicado no:Int J Neuropsychopharmacol
Main Authors: Subbanna, Shivakumar, Nagre, Nagaraja N., Umapathy, Nagavedi S., Pace, Betty S., Basavarajappa, Balapal S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376538/
https://ncbi.nlm.nih.gov/pubmed/25609594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyu028
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