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CB1R regulates CDK5 signaling and epigenetically controls Rac1 expression contributing to neurobehavioral abnormalities in mice postnatally exposed to ethanol

Fetal alcohol spectrum disorders (FASD) represent a wide array of defects that arise from ethanol exposure during development. However, the underlying molecular mechanisms are limited. In the current report, we aimed to further evaluate the cannabinoid receptor type 1 (CB1R)-mediated mechanisms in a...

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Publicado en:Neuropsychopharmacology
Autores principales: Joshi, Vikram, Subbanna, Shivakumar, Shivakumar, Madhu, Basavarajappa, Balapal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6333777/
https://ncbi.nlm.nih.gov/pubmed/30143782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0181-y
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