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Liposome-Encapsulated CpG Enhances Antitumor Activity Accompanying the Changing of Lymphocyte Populations in Tumor via Intratumoral Administration

Although oligodeoxynucleotides containing CpG motifs (CpG-ODN) are potent immune stimulators, the use of natural CpG-ODN—phosphodiester-backbone CpG—has been limited due to its instability by nuclease in vivo. The aim of this study is to investigate the anticancer efficiency of CpG-ODN capsulated us...

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Detalles Bibliográficos
Publicado en:Nucleic Acid Ther
Main Authors: Kim, Dong Hyeok, Moon, Chaerin, Oh, Sang-Seok, Park, Soojong, Jeong, Jin-Woo, Kim, Suk, Lee, Hee Gu, Kwon, Hyung-Joo, Kim, Kwang Dong
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376490/
https://ncbi.nlm.nih.gov/pubmed/25692533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/nat.2014.0509
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