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A novel mechanism for cytoprotection against hypoxic injury: δ–opioid receptor-mediated increase in Nrf2 translocation

BACKGROUND AND PURPOSE: Hypoxia/reoxygenation induces synthesis of reactive oxygen species (ROS) which can attack macromolecules and cause brain injury. The transcription factor, nuclear factor (erythroid-derived 2)-like 2, (Nrf2), ia potent activator of genes with an antioxidant responsive element...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Cao, Shan, Chao, Dongman, Zhou, Honghao, Balboni, Gianfranco, Xia, Ying
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376463/
https://ncbi.nlm.nih.gov/pubmed/25439010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13031
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