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Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury

Hepatocytes provide most liver functions, but they can also proliferate and regenerate the liver after injury. However, under some liver injury conditions, particularly chronic liver injury where hepatocyte proliferation is impaired, liver stem cells (LSCs) are thought to replenish lost hepatocytes....

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Schaub, Johanna R., Malato, Yann, Gormond, Coralie, Willenbring, Holger
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376310/
https://ncbi.nlm.nih.gov/pubmed/25131204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.07.003
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