Spermatid Head Elongation with Normal Nuclear Shaping Requires ADP-Ribosyltransferase PARP11 (ARTD11) in Mice

Sperm are highly differentiated cells characterized by their species-specific nuclear shapes and extremely condensed chromatin. Abnormal head shapes represent a form of teratozoospermia that can impair fertilization capacity. This study shows that poly(ADP-ribose) polymerase-11 (ARTD11/PARP11), a me...

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Veröffentlicht in:Biol Reprod
Hauptverfasser: Meyer-Ficca, Mirella L., Ihara, Motomasa, Bader, Jessica J., Leu, N. Adrian, Beneke, Sascha, Meyer, Ralph G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for the Study of Reproduction, Inc. 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376083/
https://ncbi.nlm.nih.gov/pubmed/25673562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.114.123661
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