A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland

Progesterone drives mammary stem and progenitor cell dynamics through paracrine mechanisms that are currently not well understood. Here, we demonstrate that CXCR4, the receptor for stromal-derived factor 1 (SDF-1; CXC12), is a crucial instructor of hormone-induced mammary stem and progenitor cell fu...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Shiah, Yu-Jia, Tharmapalan, Pirashaanthy, Casey, Alison E., Joshi, Purna A., McKee, Trevor D., Jackson, Hartland W., Beristain, Alexander G., Chan-Seng-Yue, Michelle A., Bader, Gary D., Lydon, John P., Waterhouse, Paul D., Boutros, Paul C., Khokha, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376056/
https://ncbi.nlm.nih.gov/pubmed/28447939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.01.011
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