A Progesterone-CXCR4 Axis Controls Mammary Progenitor Cell Fate in the Adult Gland

Progesterone drives mammary stem and progenitor cell dynamics through paracrine mechanisms that are currently not well understood. Here, we demonstrate that CXCR4, the receptor for stromal-derived factor 1 (SDF-1; CXC12), is a crucial instructor of hormone-induced mammary stem and progenitor cell fu...

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Foilsithe in:Stem Cell Reports
Main Authors: Shiah, Yu-Jia, Tharmapalan, Pirashaanthy, Casey, Alison E., Joshi, Purna A., McKee, Trevor D., Jackson, Hartland W., Beristain, Alexander G., Chan-Seng-Yue, Michelle A., Bader, Gary D., Lydon, John P., Waterhouse, Paul D., Boutros, Paul C., Khokha, Rama
Formáid: Artigo
Teanga:Inglês
Foilsithe: Elsevier 2015
Ábhair:
Report
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376056/
https://ncbi.nlm.nih.gov/pubmed/28447939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.01.011
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