Novel Cycloheximide Derivatives Targeting the Moonlighting Protein Mip Exhibit Specific Antimicrobial Activity Against Legionella pneumophila

Macrophage infectivity potentiator (Mip) and Mip-like proteins are virulence factors in a wide range of pathogens including Legionella pneumophila. These proteins belong to the FK506 binding protein (FKBP) family of peptidyl-prolyl-cis/trans-isomerases (PPIases). In L. pneumophila, the PPIase activi...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Bioeng Biotechnol
Main Authors: Rasch, Janine, Theuerkorn, Martin, Ünal, Can, Heinsohn, Natascha, Tran, Stefan, Fischer, Gunter, Weiwad, Matthias, Steinert, Michael
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2015
Teme:
Bioengineering and Biotechnology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376002/
https://ncbi.nlm.nih.gov/pubmed/25870856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2015.00041
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki