The BET Family Member BRD4 Interacts with OCT4 and Regulates Pluripotency Gene Expression

Embryonic stem cell (ESC) pluripotency is controlled by defined transcription factors. During cellular differentiation, ESCs undergo a global epigenetic reprogramming. Female ESCs exemplify this process as one of the two X-chromosomes is globally silenced during X chromosome inactivation (XCI) to ba...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Wu, Tao, Pinto, Hugo Borges, Kamikawa, Yasunao F., Donohoe, Mary E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375790/
https://ncbi.nlm.nih.gov/pubmed/25684227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.01.012
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