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The BET Family Member BRD4 Interacts with OCT4 and Regulates Pluripotency Gene Expression
Embryonic stem cell (ESC) pluripotency is controlled by defined transcription factors. During cellular differentiation, ESCs undergo a global epigenetic reprogramming. Female ESCs exemplify this process as one of the two X-chromosomes is globally silenced during X chromosome inactivation (XCI) to ba...
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Publicado no: | Stem Cell Reports |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Elsevier
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375790/ https://ncbi.nlm.nih.gov/pubmed/25684227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.01.012 |
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