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Fundamental origins and limits for scaling a maternal morphogen gradient

Tissue expansion and patterning are integral to development, but it is unknown quantitatively how a mother accumulates molecular resources to invest in the future of instructing robust embryonic patterning. Here we develop a model, Tissue Expansion-Modulated Maternal Morphogen Scaling (TEM(3)S), to...

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發表在:Nat Commun
Main Authors: He, Feng, Wei, Chuanxian, Wu, Honggang, Cheung, David, Jiao, Renjie, Ma, Jun
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375784/
https://ncbi.nlm.nih.gov/pubmed/25809405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7679
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