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Evaluating the Drosophila Bicoid morphogen gradient system through dissecting the noise in transcriptional bursts
Motivation: We describe a statistical model to dissect the noise in transcriptional bursts in a developmental system. Results: We assume that, at any given moment of time, each copy of a native gene inside a cell can exist in either a bursting (active) or non-bursting (inactive) state. The experimen...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3315720/ https://ncbi.nlm.nih.gov/pubmed/22302571 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts068 |
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