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Evaluating the Drosophila Bicoid morphogen gradient system through dissecting the noise in transcriptional bursts

Motivation: We describe a statistical model to dissect the noise in transcriptional bursts in a developmental system. Results: We assume that, at any given moment of time, each copy of a native gene inside a cell can exist in either a bursting (active) or non-bursting (inactive) state. The experimen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: He, Feng, Ren, Jie, Wang, Wei, Ma, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315720/
https://ncbi.nlm.nih.gov/pubmed/22302571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bts068
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