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Current and future targeted therapies for non-small-cell lung cancers with aberrant EGF receptors

Expression of the EGF receptors (EGFRs) is abnormally high in many types of cancer, including 25% of lung cancers. Successful treatments target mutations in the EGFR tyrosine kinase domain with EGFR tyrosine kinase inhibitors (TKIs). However, almost all patients develop resistance to this treatment,...

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Publicat a:Future Oncol
Autors principals: Kanthala, Shanthi, Pallerla, Sandeep, Jois, Seetharama
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375777/
https://ncbi.nlm.nih.gov/pubmed/25757687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.14.312
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