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The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia
PAX5-JAK2 has recently been identified as a novel recurrent fusion gene in B-cell precursor acute lymphoblastic leukemia, but the function of the encoded chimeric protein has not yet been characterized in detail. Herein we show that the PAX5-JAK2 chimera, which consists of the DNA-binding paired dom...
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| Publicado no: | Blood |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4375719/ https://ncbi.nlm.nih.gov/pubmed/25515960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-570960 |
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