Capsaicin Interaction with TRPV1 Channels in a Lipid Bilayer: Molecular Dynamics Simulation

Transient receptor potential vanilloid subtype 1 (TRPV1) is a heat-sensitive ion channel also involved in pain sensation, and is the receptor for capsaicin, the active ingredient of hot chili peppers. The recent structures of TRPV1 revealed putative ligand density within the S1 to S4 voltage-sensor-...

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Bibliografiske detaljer
Udgivet i:Biophys J
Main Authors: Hanson, Sonya M., Newstead, Simon, Swartz, Kenton J., Sansom, Mark S.P.
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2015
Fag:
Channels and Transporters
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375533/
https://ncbi.nlm.nih.gov/pubmed/25809255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.013
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