How pH Modulates the Dimer-Decamer Interconversion of 2-Cys Peroxiredoxins from the Prx1 Subfamily

2-Cys peroxiredoxins belonging to the Prx1 subfamily are Cys-based peroxidases that control the intracellular levels of H(2)O(2) and seem to assume a chaperone function under oxidative stress conditions. The regulation of their peroxidase activity as well as the observed functional switch from perox...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Morais, Mariana A. B., Giuseppe, Priscila O., Souza, Tatiana A. C. B., Alegria, Thiago G. P., Oliveira, Marcos A., Netto, Luis E. S., Murakami, Mario T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2015
Schlagworte:
Protein Structure and Folding
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375507/
https://ncbi.nlm.nih.gov/pubmed/25666622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.619205
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