Calcium and magnesium ions modulate the oligomeric state and function of mitochondrial 2-Cys peroxiredoxins in Leishmania parasites

Leishmania parasites have evolved a number of strategies to cope with the harsh environmental changes during mammalian infection. One of these mechanisms involves the functional gain that allows mitochondrial 2-Cys peroxiredoxins to act as molecular chaperones when forming decamers. This function is...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Morais, Mariana A. B., Giuseppe, Priscila O., Souza, Tatiana A. C. B., Castro, Helena, Honorato, Rodrigo V., Oliveira, Paulo S. L., Netto, Luis E. S., Tomas, Ana M., Murakami, Mario T.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409470/
https://ncbi.nlm.nih.gov/pubmed/28292930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.762039
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