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Lipid Binding Defects and Perturbed Synaptogenic Activity of a Collybistin R290H Mutant That Causes Epilepsy and Intellectual Disability

Signaling at nerve cell synapses is a key determinant of proper brain function, and synaptic defects—or synaptopathies—are at the basis of many neurological and psychiatric disorders. In key areas of the mammalian brain, such as the hippocampus or the basolateral amygdala, the clustering of the scaf...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Papadopoulos, Theofilos, Schemm, Rudolf, Grubmüller, Helmut, Brose, Nils
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375481/
https://ncbi.nlm.nih.gov/pubmed/25678704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633024
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