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Lipid Binding Defects and Perturbed Synaptogenic Activity of a Collybistin R290H Mutant That Causes Epilepsy and Intellectual Disability

Signaling at nerve cell synapses is a key determinant of proper brain function, and synaptic defects—or synaptopathies—are at the basis of many neurological and psychiatric disorders. In key areas of the mammalian brain, such as the hippocampus or the basolateral amygdala, the clustering of the scaf...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Papadopoulos, Theofilos, Schemm, Rudolf, Grubmüller, Helmut, Brose, Nils
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375481/
https://ncbi.nlm.nih.gov/pubmed/25678704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.633024
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