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Chronopharmacokinetics of once daily dosed aminoglycosides in hospitalized infectious patients

Background hospitalized patients with serious infections treated with aminoglycosides are at risk of developing nephrotoxicity. Previous clinical studies have shown that the pharmacokinetics of aminoglycosides in humans follow a circadian rhythm. Therefore, the time of administration could have impo...

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Detalles Bibliográficos
Publicado en:Int J Clin Pharm
Main Authors: van Maarseveen, Erik, Man, Wai Hong, Proost, Johannes, Neef, Cees, Touw, Daniël
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375292/
https://ncbi.nlm.nih.gov/pubmed/25616626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11096-015-0066-7
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