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Chronopharmacokinetics of once daily dosed aminoglycosides in hospitalized infectious patients

Background hospitalized patients with serious infections treated with aminoglycosides are at risk of developing nephrotoxicity. Previous clinical studies have shown that the pharmacokinetics of aminoglycosides in humans follow a circadian rhythm. Therefore, the time of administration could have impo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Clin Pharm
Hauptverfasser: van Maarseveen, Erik, Man, Wai Hong, Proost, Johannes, Neef, Cees, Touw, Daniël
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Netherlands 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375292/
https://ncbi.nlm.nih.gov/pubmed/25616626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11096-015-0066-7
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