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Tandem Duplication of Exons 1–7 Neither Impairs ATP7A Expression Nor Causes a Menkes Disease Phenotype

ATP7A duplications are estimated to represent the molecular cause of Menkes disease in 4–10% of affected patients. We identified a novel duplication of ATP7A exons 1–7 discovered in the context of a challenging prenatal diagnostic situation. All other reported ATP7A duplications (n = 24) involved in...

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Pubblicato in:JIMD Rep
Autori principali: Choi, Eun-Young, Patel, Keyur, Haddad, Marie Reine, Yi, Ling, Holmes, Courtney, Goldstein, David S., Dutra, Amalia, Pak, Evgenia, Kaler, Stephen G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375122/
https://ncbi.nlm.nih.gov/pubmed/25638460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2014_391
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