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Lack of Glibenclamide Response in a Case of Permanent Neonatal Diabetes Caused by Incomplete Inactivation of Glucokinase

Background: Hypoglycaemic drugs that close the K(ATP) channel have been tested in patients with permanent neonatal diabetes due to glucokinase mutations (PNDM-GCK). From the results obtained, it has been suggested that this treatment may be beneficial in patients carrying GCK mutations with mild kin...

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Detalhes bibliográficos
Publicado no:JIMD Rep
Main Authors: Oriola, Josep, Moreno, Francisca, Gutiérrez-Nogués, Angel, León, Sara, García-Herrero, Carmen-María, Vincent, Olivier, Navas, María-Angeles
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375116/
https://ncbi.nlm.nih.gov/pubmed/25665835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2014_383
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