Noncanonical Wnt Signaling Promotes Obesity-Induced Adipose Tissue Inflammation and Metabolic Dysfunction Independent of Adipose Tissue Expansion

Adipose tissue dysfunction plays a pivotal role in the development of insulin resistance in obese individuals. Cell culture studies and gain-of-function mouse models suggest that canonical Wnt proteins modulate adipose tissue expansion. However, no genetic evidence supports a role for endogenous Wnt...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Diabetes
Hauptverfasser: Fuster, José J., Zuriaga, María A., Ngo, Doan Thi-Minh, Farb, Melissa G., Aprahamian, Tamar, Yamaguchi, Terry P., Gokce, Noyan, Walsh, Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2015
Schlagworte:
Obesity Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375084/
https://ncbi.nlm.nih.gov/pubmed/25352637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1164
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge