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TLR2- and Dectin 1–Associated Innate Immune Response Modulates T-Cell Response to Pancreatic β-Cell Antigen and Prevents Type 1 Diabetes

The progression of autoimmune diseases is dictated by deviations in the fine balance between proinflammatory versus regulatory responses, and pathogen recognition receptors (PRRs) play a key role in maintaining this balance. Previously, we have reported that ligation of Toll-like receptor 2 (TLR2) a...

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Vydáno v:Diabetes
Hlavní autoři: Karumuthil-Melethil, Subha, Sofi, M. Hanief, Gudi, Radhika, Johnson, Benjamin M., Perez, Nicolas, Vasu, Chenthamarakshan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375080/
https://ncbi.nlm.nih.gov/pubmed/25377877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db14-1145
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