Identification of the Neutralizing Epitopes of Merkel Cell Polyomavirus Major Capsid Protein within the BC and EF Surface Loops

Merkel cell polyomavirus (MCPyV) is the first polyomavirus clearly associated with a human cancer, i.e. the Merkel cell carcinoma (MCC). Polyomaviruses are small naked DNA viruses that induce a robust polyclonal antibody response against the major capsid protein (VP1). However, the polyomavirus VP1...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Fleury, Maxime J. J., Nicol, Jérôme T. J., Samimi, Mahtab, Arnold, Françoise, Cazal, Raphael, Ballaire, Raphaelle, Mercey, Olivier, Gonneville, Hélène, Combelas, Nicolas, Vautherot, Jean-Francois, Moreau, Thierry, Lorette, Gérard, Coursaget, Pierre, Touzé, Antoine
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374900/
https://ncbi.nlm.nih.gov/pubmed/25812141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121751
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