Identification of the neutralizing epitopes of Merkel cell polyomavirus major capsid protein within the BC and EF surface loops.

Merkel cell polyomavirus (MCPyV) is the first polyomavirus clearly associated with a human cancer, i.e. the Merkel cell carcinoma (MCC). Polyomaviruses are small naked DNA viruses that induce a robust polyclonal antibody response against the major capsid protein (VP1). However, the polyomavirus VP1...

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Main Authors: Maxime J J Fleury, Jérôme T J Nicol, Mahtab Samimi, Françoise Arnold, Raphael Cazal, Raphaelle Ballaire, Olivier Mercey, Hélène Gonneville, Nicolas Combelas, Jean-Francois Vautherot, Thierry Moreau, Gérard Lorette, Pierre Coursaget, Antoine Touzé
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-01-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC4374900?pdf=render
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