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Removal of Endotoxins from Bacteriophage Preparations by Extraction with Organic Solvents

Lipopolysaccharide (LPS, endotoxin, pyrogen) constitutes a very troubling contaminant of crude phage lysates produced in Gram-negative bacteria. Toxicity of LPS depends on the strong innate immunity response including the cytokines. Therefore, its removal is important for bacteriophage applications....

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Foilsithe in:PLoS One
Main Authors: Szermer-Olearnik, Bożena, Boratyński, Janusz
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374689/
https://ncbi.nlm.nih.gov/pubmed/25811193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122672
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