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Removal of Endotoxins from Bacteriophage Preparations by Extraction with Organic Solvents
Lipopolysaccharide (LPS, endotoxin, pyrogen) constitutes a very troubling contaminant of crude phage lysates produced in Gram-negative bacteria. Toxicity of LPS depends on the strong innate immunity response including the cytokines. Therefore, its removal is important for bacteriophage applications....
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Publicado no: | PLoS One |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374689/ https://ncbi.nlm.nih.gov/pubmed/25811193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122672 |
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