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Coating solid dispersions on microneedles via a molten dip coating method: development and in vitro evaluation for transdermal delivery of a water insoluble drug

This study demonstrates for the first time the ability to coat solid dispersions on microneedles as a means to deliver water-insoluble drugs through the skin. Polyethylene glycol (PEG) was selected as the hydrophilic matrix, and lidocaine base was selected as the model hydrophobic drug to create the...

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Vydáno v:J Pharm Sci
Hlavní autoři: Ma, Yunzhe, Gill, Harvinder S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374630/
https://ncbi.nlm.nih.gov/pubmed/25213295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.24159
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