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Vaccine delivery to the oral cavity using coated microneedles induces systemic and mucosal immunity

PURPOSE: The objective of this study is to evaluate the feasibility of using coated microneedles to deliver vaccines into the oral cavity to induce systemic and mucosal immune responses. METHOD: Microneedles were coated with sulforhodamine, ovalbumin and two HIV antigens. Coated microneedles were in...

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Detalhes bibliográficos
Main Authors: Ma, Yunzhe, Tao, Wenqian, Krebs, Shelly J., Sutton, William F., Haigwood, Nancy L., Gill, Harvinder S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163144/
https://ncbi.nlm.nih.gov/pubmed/24623480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-014-1335-1
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