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Quantitative trait loci affecting the 3D skull shape and size in mouse and prioritization of candidate genes in-silico

We describe the first application of high-resolution 3D micro-computed tomography, together with 3D landmarks and geometric morphometrics, to map QTL responsible for variation in skull shape and size using a backcross between C57BL/6J and A/J inbred strains. Using 433 animals, 53 3D landmarks, and 8...

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Publicat a:Front Physiol
Autors principals: Maga, A. Murat, Navarro, Nicolas, Cunningham, Michael L., Cox, Timothy C.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374467/
https://ncbi.nlm.nih.gov/pubmed/25859222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00092
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