Functional and structural deficits at accumbens synapses in a mouse model of Fragile X

Fragile X is the most common cause of inherited intellectual disability and a leading cause of autism. The disease is caused by mutation of a single X-linked gene called fmr1 that codes for the Fragile X mental retardation protein (FMRP), a 71 kDa protein, which acts mainly as a translation inhibito...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Neurosci
Prif Awduron: Neuhofer, Daniela, Henstridge, Christopher M., Dudok, Barna, Sepers, Marja, Lassalle, Olivier, Katona, István, Manzoni, Olivier J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2015
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374460/
https://ncbi.nlm.nih.gov/pubmed/25859182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2015.00100
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