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Using C. elegans to Identify the Protease Targets of Serpins In Vivo
Most serpins inhibit serine and/or cysteine proteases, and their inhibitory activities are usually defined in vitro. However, the physiological protease targets of most serpins are unknown despite many years of research. This may be due to the rapid degradation of the inactive serpin:protease comple...
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| Veröffentlicht in: | Methods Enzymol |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374438/ https://ncbi.nlm.nih.gov/pubmed/21683259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-386471-0.00014-6 |
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