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Characterization of Thioether-Linked Protein Adducts of DNA Using a Raney-Ni Mediated Desulfurization Method and Liquid Chromatography-Electrospray-Tandem Mass Spectrometry

This unit contains a complete procedure for the detection and structural characterization of DNA protein crosslinks (DPCs). The procedure also describes an approach for the quantitation of the various structurally distinct DPCs. Although various methods have been described in the literature for labi...

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Dettagli Bibliografici
Pubblicato in:Curr Protoc Nucleic Acid Chem
Autori principali: Chowdhury, Goutam, Guengerich, F. Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374425/
https://ncbi.nlm.nih.gov/pubmed/25754888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/0471142700.nc1015s60
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