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Decoding the Regulatory Network for Blood Development from Single-Cell Gene Expression Measurements

Here we report the use of diffusion maps and network synthesis from state transition graphs to better understand developmental pathways from single cell gene expression profiling. We map the progression of mesoderm towards blood in the mouse by single-cell expression analysis of 3,934 cells, capturi...

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Detaylı Bibliyografya
Yayımlandı:Nat Biotechnol
Asıl Yazarlar: Moignard, Victoria, Woodhouse, Steven, Haghverdi, Laleh, Lilly, Andrew J., Tanaka, Yosuke, Wilkinson, Adam C., Buettner, Florian, Macaulay, Iain C., Jawaid, Wajid, Diamanti, Evangelia, Nishikawa, Shin-Ichi, Piterman, Nir, Kouskoff, Valerie, Theis, Fabian J., Fisher, Jasmin, Göttgens, Berthold
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374163/
https://ncbi.nlm.nih.gov/pubmed/25664528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3154
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