Decoding the Regulatory Network for Blood Development from Single-Cell Gene Expression Measurements

Here we report the use of diffusion maps and network synthesis from state transition graphs to better understand developmental pathways from single cell gene expression profiling. We map the progression of mesoderm towards blood in the mouse by single-cell expression analysis of 3,934 cells, capturi...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Moignard, Victoria, Woodhouse, Steven, Haghverdi, Laleh, Lilly, Andrew J., Tanaka, Yosuke, Wilkinson, Adam C., Buettner, Florian, Macaulay, Iain C., Jawaid, Wajid, Diamanti, Evangelia, Nishikawa, Shin-Ichi, Piterman, Nir, Kouskoff, Valerie, Theis, Fabian J., Fisher, Jasmin, Göttgens, Berthold
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374163/
https://ncbi.nlm.nih.gov/pubmed/25664528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3154
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