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Decoding the Regulatory Network for Blood Development from Single-Cell Gene Expression Measurements

Here we report the use of diffusion maps and network synthesis from state transition graphs to better understand developmental pathways from single cell gene expression profiling. We map the progression of mesoderm towards blood in the mouse by single-cell expression analysis of 3,934 cells, capturi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Biotechnol
Egile Nagusiak: Moignard, Victoria, Woodhouse, Steven, Haghverdi, Laleh, Lilly, Andrew J., Tanaka, Yosuke, Wilkinson, Adam C., Buettner, Florian, Macaulay, Iain C., Jawaid, Wajid, Diamanti, Evangelia, Nishikawa, Shin-Ichi, Piterman, Nir, Kouskoff, Valerie, Theis, Fabian J., Fisher, Jasmin, Göttgens, Berthold
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374163/
https://ncbi.nlm.nih.gov/pubmed/25664528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3154
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