Загрузка...
TopBP1 Interacts with BLM to Maintain Genome Stability but Is Dispensable for Preventing BLM Degradation
The Bloom syndrome helicase BLM and topoisomerase-IIβ-binding protein 1 (TopBP1) are key regulators of genome stability. It was recently proposed that BLM phosphorylation on Ser338 mediates its interaction with TopBP1, to protect BLM from ubiquitylation and degradation (Wang et al., 2013). Here, we...
Сохранить в:
| Опубликовано в: : | Mol Cell |
|---|---|
| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cell Press
2015
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374139/ https://ncbi.nlm.nih.gov/pubmed/25794620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.02.012 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|