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Cilia and Polycystic Kidney Disease, Kith and Kin

In the past decade, cilia have been found to play important roles in renal cystogenesis. Many genes, such as PKD1 and PKD2 which, when mutated, cause autosomal dominant polycystic kidney disease (ADPKD), have been found to localize to primary cilia. The cilium functions as a sensor to transmit extra...

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Detalhes bibliográficos
Publicado no:Birth Defects Res C Embryo Today
Main Authors: Huang, Liwei, Lipschutz, Joshua H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374053/
https://ncbi.nlm.nih.gov/pubmed/24898006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bdrc.21066
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