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A Possible Zebrafish Model of Polycystic Kidney Disease: Knockdown of wnt5a Causes Cysts in Zebrafish Kidneys

Polycystic kidney disease (PKD) is one of the most common causes of end-stage kidney disease, a devastating disease for which there is no cure. The molecular mechanisms leading to cyst formation in PKD remain somewhat unclear, but many genes are thought to be involved. Wnt5a is a non-canonical glyco...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Huang, Liwei, Xiao, An, Wecker, Andrea, McBride, Daniel A., Choi, Soo Young, Zhou, Weibin, Lipschutz, Joshua H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354438/
https://ncbi.nlm.nih.gov/pubmed/25489842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52156
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