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Antibacterial Properties and Atomic Resolution X-Ray Complex Crystal Structure of a Ruthenocene Conjugated β-Lactam Antibiotic
We have determined a 1.18 Å resolution X-ray crystal structure of a novel ruthenocenyle-6-aminopenicillinic acid in complex with CTX-M β-lactamase, showing unprecedented details of interactions between ruthenocene and protein. As the first product complex with an intact catalytic serine, the structu...
Guardat en:
| Publicat a: | Chem Commun (Camb) |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374039/ https://ncbi.nlm.nih.gov/pubmed/25753149 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc00904a |
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