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Loss of PLZF Expression in Prostate Cancer by Immunohistochemistry Correlates with Tumor Aggressiveness and Metastasis

PLZF is a transcription repressor, which plays a critical role in development, spermatogenesis and oncogenesis. Down-regulation of PLZF has been found in various tumor cell lines. There has been virtually no tissue study on the expression of PLZF in prostate cancer (PCa). PCa is a heterogeneous dise...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Xiao, Guang-Qian, Unger, Pamela, Yang, Qi, Kinoshita, Yayoi, Singh, Kyra, McMahon, Loralee, Nastiuk, Kent, Sha, Kai, Krolewski, John, Burstein, David
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373907/
https://ncbi.nlm.nih.gov/pubmed/25807461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121318
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