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Zip4 Mediated Zinc Influx Stimulates Insulin Secretion in Pancreatic Beta Cells

Zinc has an important role in normal pancreatic beta cell physiology as it regulates gene transcription, insulin crystallization and secretion, and cell survival. Nevertheless, little is known about how zinc is transported through the plasma membrane of beta cells and which of the class of zinc infl...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Hardy, Alexandre B., Prentice, Kacey J., Froese, Sean, Liu, Ying, Andrews, Glen K., Wheeler, Michael B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373830/
https://ncbi.nlm.nih.gov/pubmed/25806541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119136
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