Characterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION

Zinc plays an essential role in the regulation of pancreatic β cell function, affecting important processes including insulin biosynthesis, glucose-stimulated insulin secretion, and cell viability. Mutations in the zinc efflux transport protein ZnT8 have been linked with both type 1 and type 2 diabe...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Liu, Ying, Batchuluun, Battsetseg, Ho, Louisa, Zhu, Dan, Prentice, Kacey J., Bhattacharjee, Alpana, Zhang, Ming, Pourasgari, Farzaneh, Hardy, Alexandre B., Taylor, Kathryn M., Gaisano, Herbert, Dai, Feihan F., Wheeler, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4513131/
https://ncbi.nlm.nih.gov/pubmed/25969539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.640524
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