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Tumor Angiogenesis in the Absence of Fibronectin or Its Cognate Integrin Receptors
Binding of α5β1 and αvβ3/β5 integrin receptors on the endothelium to their fibronectin substrate in the extracellular matrix has been targeted as a possible means of blocking tumor angiogenesis and tumor growth. However, clinical trials of blocking antibodies and peptides have been disappointing des...
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| Veröffentlicht in: | PLoS One |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4373772/ https://ncbi.nlm.nih.gov/pubmed/25807551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120872 |
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